Grant Publications

Proposal No.   IBD-0067R
Principal Investigator:  Daniel C. Baumgart, M.D., Ph.D.
Applicant Organization:  Charité Medical Center - Medical School of the Humboldt - University of Berlin (Germany)
Project Title: Dendritic cells in inflammatory bowel disease
Period of Award:  September 1, 2003 - March 31, 2006

Baumgart DC, Metzke D, Schmitz J, Scheffold A, Sturm A, Wiedenmann B, Dignass AU.  Patients with active inflammatory bowel disease lack immature peripheral blood plasmacytoid and myeloid dendritic cells.  Gut 2005;54:228-36.

Andresen V, Baumgart DC.  Role of probiotics in the treatment of irritable bowel syndrome:  potential mechanisms and current clinical evidence.  International Journal of Probiotics and Prebiotics 2006;1:11-8.

Baumgart DC, Buning C, Geerdts L, Schmidt HH, Genschel F, Fiedler T, Gentz E, Molnar T, et al.  The c.1-260C>T promoter variant of CD14 but not the c.896A>G (p.D299G) variant of toll-like receptor 4 (TLR4) genes is associated with inflammatory bowel disease.  Digestion 2007;76:196-202.

Baumgart DC, Carding SD.  Inflammatory bowel disease: cause and immunobiology. Lancet 2007;369:1627-40.

Baumgart DC, Sandborn WJ.  Inflammatory bowel disease: clinical aspects and established and evolving therapies. Lancet 2007;369:1641-57.

Weylandt KH, Kang JX, Wiedenmann B, Baumgart DC. Lipoxins and resolvins in inflammatory bowel disease. Inflammatory Bowel Diseases 2007;6:797-9.

Baumgart DC, Thomas S, Przesdzing I, Metzke D, Bielecki C, Lehmann SM, Lehnardt S, Doerffel Y, et al.  Exaggerated inflammatory response of primary human myeloid dendritic cells to lipopolysaccharide in patients with inflammatory bowel disease.  Clinical and Experimental Immunology 2009;157:423-36.

Thomas S, Przesdzing I, Metzke D, Schmitz J, Radbruch A, Baumgart DC.  Saccharomyces boulardii inhibits lipopolysaccharide-induced activation of human dendritic cells and T cell proliferation.  Clinical and Experimental Immunology 2009;56:78-87.