Grants Funded in 2006
Principal Investigator: Büning, Carsten, M.D.
Proposal No. IBD-0164R
Applicant Organization: Charité, Campus Mitte, Universitätsmedizin Berlin (Germany)
Project Title: Genes involved in epithelial integrity as risk factors for inflammatory bowel disease?
Period of Award: June 1, 2006 – November 30, 2007
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Principal Investigator: Chiorean, Michael V., M.D.
Proposal No. IBD-0179R
Applicant Organization: Indiana University (U.S.A.)
Project Title: Correlation of CT enteroclysis with surgical pathology in patients with Crohn’s disease
Period of Award: April 1, 2006 – March 31, 2007
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Principal Investigator: Clandinin, Michael T., Ph.D.
Proposal No. IBD-0162R
Applicant Organization: University of Alberta (Canada)
Project Title: Milk-derived gangliosides as novel anti-inflammatory therapy for inflammatory bowel disease
Period of Award: March 1, 2006 – August 31, 2008
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Principal Investigator: Craig, Robert M., M.D.
Proposal No. IBD-0170R
Applicant Organization: Northwestern University (U.S.A.)
Project Title: Immune ablation and hematopoietic stem cell support in patients with refractory Crohn’s. A randomized, controlled study.
Period of Award: June 1, 2006 – September 30, 2008
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Principal Investigator: Cross, Raymond K., M.D.
Proposal No. IBD-0190
Applicant Organization: University of Maryland (U.S.A.)
Project Title: Home telemanagement trial (UC HAT) in patients with ulcerative colitis
Period of Award: October 1, 2006 – June 30, 2010
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Principal Investigator: Fortun, Paul J., BM BCh
Proposal No. IBD-0184
Applicant Organization: University of Nottingham (United Kingdom)
Project Title: Hookworm infestation as therapy in Crohn's disease
Period of Award: August 14, 2006 – August 13, 2008
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Principal Investigator: Hale, Laura P., M.D., Ph.D.
Proposal No. IBD-0171R
Applicant Organization: Duke University (U.S.A.)
Project Title: Therapy of inflammatory bowel disease using LMP-420
Period of Award: March 1, 2006 – February 28, 2007
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Principal Investigator: Hawkey, Christopher J., DM
Proposal No. IBD-0155
Applicant Organization: University of Nottingham (United Kingdom)
Project Title: Autologous stem cell transplantation: international Crohn’s syndrome (ASTICS) trial
Period of Award: March 1, 2006 – December 31, 2009
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Principal Investigator: Hold, Georgina L., Ph.D.
Proposal No. IBD-0178
Applicant Organization: University of Aberdeen (United Kingdom)
Project Title: Assessment of non-pylori Helicobacter species in ulcerative colitis
Period of Award: July 1, 2006 – September 30, 2010
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Principal Investigator: Hugot, Jean-Pierre, M.D., Ph.D.
Proposal No. IBD-0157R2
Applicant Organization: Naturalia et Biologia (France)
Project Title: Role of psychrotrophic bacteria in Crohn's disease
Period of Award: May 1, 2006 – October 31, 2007
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Principal Investigator: Ikuma, Mutsuhiro, M.D., Ph.D. (Former Principal Investigator: Koide, Yukio, M.D., Ph.D.)
Proposal No. IBD-0191
Applicant Organization: Hamamatsu University (Japan)
Project Title: A randomized clinical trial of curcumin in the therapy of ulcerative colitis
Period of Award: November 1, 2006 - April 30, 2009
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Principal Investigator: Kokkotou, Efi G., M.D., Ph.D.
Proposal No. IBD-0165R
Applicant Organization: Beth Israel Deaconess Medical Center, Inc. (U.S.A.)
Project Title: Targeting melanin concentrating hormone as a novel treatment for inflammatory bowel disease
Period of Award: January 1, 2006 – December 31, 2007
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Principal Investigator: Lindsay, James O., BM BCh, Ph.D.
Proposal No. IBD-0166R
Applicant Organization: King's College London (United Kingdom)
Project Title: Fructo-oligosaccharides and Crohn’s disease: a prospective, randomized, double-blind controlled trial
Period of Award: August 7, 2006 – December 31, 2009
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Principal Investigator: Mahadevan, Uma, M.D.
Proposal No. IBD-0173
Applicant Organization: University of California, San Francisco (U.S.A.)
Project Title: Genetic damage to sperm following treatment with azathioprine/6-mercaptopurine in men with inflammatory bowel disease
Period of Award: January 1, 2006 – February 29, 2008
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Principal Investigator: Mitchell, Hazel M., Ph.D.
Proposal No. IBD-0183
Applicant Organization: The University of New South Wales (Australia)
Project Title: Investigation of the role of members of the Helicobacteriaceae in Crohn’s disease
Period of Award: September 7, 2006 – March 6, 2008
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Principal Investigator: Orchard, Timothy, M.D.
Proposal No. IBD-0187
Applicant Organization: Imperial College of Science, Technology and Medicine (United Kingdom)
Project Title: The use of metabonomic technology (nuclear magnetic resonance spectroscopy) in the investigation of Crohn’s disease
Period of Award: September 1, 2006 – August 31, 2009
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Principal Investigator: Smith, Jill P., M.D.
Proposal No. IBD-0180R
Applicant Organization: The Pennsylvania State University (U.S.A.)
Project Title: Effects of naltrexone on active Crohn's disease
Period of Award: August 1, 2006 – February 28, 2009
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Principal Investigator: Tsao, Stephen K. K., MBChB
Proposal No. IBD-0172R
Applicant Organization: University Hospitals of Leicester NHS Trust (United Kingdom)
Project Title: Epidermal growth factor - an alternative therapy in ulcerative colitis
Period of Award: December 1, 2006 – November 30, 2008
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Principal Investigator: van den Berg, Anke, Ph.D.
Proposal No. IBD-0158
Applicant Organization: University Medical Center Groningen (The Netherlands)
Project Title: Stable galectin-1 homodimer as a novel therapeutic agent in the treatment of inflammatory bowel disease
Period of Award: February 1, 2006 – March 31, 2008
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Principal Investigator: Xiong, Huabao, Ph.D.
Proposal No. IBD-0176R
Applicant Organization: Mount Sinai School of Medicine (U.S.A.)
Project Title: Blocking TLR signaling pathway by TLR peptides in the treatment of colitis
Period of Award: March 15, 2006 – March 14, 2008
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Principal Investigator: Ziegler, Steven F., Ph.D.
Proposal No. IBD-0185
Applicant Organization: Benaroya Research Institute at Virginia Mason (U.S.A.)
Project Title: Regulatory T cells in inflammatory bowel disease
Period of Award: August 1, 2006 – May 31, 2008
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