Grant Publications

Proposal No. IBD-0201R
Principal Investigator:  Dirk Föll, M.D.
Applicant Organization:  University Hospital of Münster (Germany)
Project Title:  Functional characterization of GM-CSF induced monocyte subsets and analysis of their relevance in Crohn's disease
Period of Award:  September 1, 2007 - August 31, 2010

Foell D, Wittkowski H, Ren Z, Turton J, Pang G, Daebritz J, Ehrchen J, Heidemann J, Borody T, Roth J, Clancy R.  Phagocyte-specific S100 proteins are released from affected mucosa and promote immune responses during inflammatory bowel disease.  Journal of Pathology 2008;216:183-92.

Sinha P, Foell D, Freeze HH, Srikrishna G, Ostrand-Rosenberg S.  Pro-inflammatory S100 proteins regulate the accumulation of myeloid-derived suppressor cells.  Journal of Immunology 2008;181:4666-75.

Turovskaya O, Foell D, Sinha P, Vogl T, Newlin R, Nayak J, Nguyen M, Olsson A, Nawroth PP, Bierhaus A, Varki N, Kronenberg M, Freeze HH, Srikrishna G.  RAGE, carboxylated glycans and S100A8/A9 play essential roles in colitis-associated carcinogenesis.  Carcinogenesis 2008;29:2035-43.

Foell D, Wittkowski H, Roth J.  Monitoring disease activity by stool analyses: from occult blood to molecular markers of intestinal inflammation and damage.  Gut 2009;58:859-868.